| Gene Information | |
|---|---|
| Gene Name | EDEM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 657 |
| Protein Names | ER degradation-enhancing alpha-mannosidase-like protein 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000134109 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q92611 |
| Gene Card | EDEM1 |
| Uniprot ID | Q92611 |
| Pfam | PF01532 |
| In ASD | no |
| Allosteric Prediction | no (-0.148231426) |
| Ortholog in Animals | Alpaca_ EDEM1 ( ortholog_one2one ) Dog_ EDEM1 ( ortholog_one2one ) GuineaPig_ EDEM1 ( ortholog_one2one ) Macaque_ EDEM1 ( ortholog_one2one ) Mouse_ Edem1 ( ortholog_one2one ) Pig_ EDEM1 ( ortholog_one2one ) Rat_ Edem1 ( ortholog_one2one ) Rabbit_ EDEM1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MAN1A2, MAN1A1, MAN1B1, EDEM2, EDEM3, MAN1C1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:19934218}; Single-pass type II membrane protein {ECO:0000269|PubMed:19934218}. |
| Mouse PG classification | NA |
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