| Gene Information | |
|---|---|
| Gene Name | CLTA |
| Organism | Homo sapiens (Human) |
| Gene Length | 248 |
| Protein Names | Clathrin light chain A (Lca) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000122705 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P09496 |
| Gene Card | CLTA |
| Uniprot ID | P09496 |
| Pfam | PF01086 |
| In ASD | no |
| Allosteric Prediction | yes (0.426882093) |
| Ortholog in Animals | Alpaca_ CLTA ( ortholog_one2one ) Dog_ CLTA ( ortholog_one2one ) GuineaPig_ CLTA ( ortholog_one2one ) Macaque_ CLTA ( ortholog_one2one ) Mouse_ Clta ( ortholog_one2one ) Pig_ CLTA ( ortholog_one2one ) Rat_ Clta ( ortholog_one2one ) Rabbit_ CLTA ( ortholog_one2one ) |
| Ohnologs | CLTB |
| Paralogs | CLTB |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001657(Rat);0.023529(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6E5N (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:21297582, ECO:0000305|PubMed:15858577}. Note=Cytoplasmic face of coated pits and vesicles. In complex with TACC3 and CKAP5 (forming the TACC3/ch-TOG/clathrin complex) localized to inter-microtubule bridges in mitotic spindles. {ECO:0000305}. |
| Mouse PG classification | NA |
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