Gene Information
Gene NameECI1
OrganismHomo sapiens (Human)
Gene Length302
Protein NamesEnoyl-CoA delta isomerase 1, mitochondrial (EC 5.3.3.8) (3,2-trans-enoyl-CoA isomerase) (Delta(3),Delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Dodecenoyl-CoA isomerase)
Target Nameenoyl-coa delta isomerase 1, mitochondrial
Target TypeNA
Gene Age1064 ( ENSG00000167969 )
Evolutionary StageEuk+Bac
AlphaFoldDBP42126
Gene CardECI1
Uniprot IDP42126
PfamPF00378
In ASDno
Allosteric Predictionno (-0.040162029)
Ortholog in AnimalsAlpaca_ ECI1 ( ortholog_one2one )
Dog_ ECI1 ( ortholog_one2one )
GuineaPig_ ECI1 ( ortholog_one2one )
Macaque_ ECI1 ( ortholog_one2one )
Mouse_ Eci1 ( ortholog_one2one )
Pig_ ECI1 ( ortholog_one2one )
Rat_ Eci1 ( ortholog_one2one )
Rabbit_ ECI1 ( ortholog_one2one )
OhnologsNA
ParalogsECHS1, AUH, ECH1, CDY1, CDYL, CDY2A, CDY2B, CDY1B, CDYL2, ECHDC3, ECHDC2, HIBCH, ECHDC1
TissueNA
Tissue SpecificityExpressed in liver (at protein level). {ECO:0000269|PubMed:7818490}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1SG4  (X-ray  1.30A 
DBSNP NA 
Subcellular location [CC]Mitochondrion matrix {ECO:0000250|UniProtKB:P23965}.
Mouse PG classificationNA
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