| Gene Information | |
|---|---|
| Gene Name | ECD |
| Organism | Homo sapiens (Human) |
| Gene Length | 644 |
| Protein Names | Protein ecdysoneless homolog (Human suppressor of GCR two) (hSGT1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000122882 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O95905 |
| Gene Card | ECD |
| Uniprot ID | O95905 |
| Pfam | PF07093 |
| In ASD | no |
| Allosteric Prediction | no (-0.266190557) |
| Ortholog in Animals | Alpaca_ ECD ( ortholog_one2one ) Dog_ ECD ( ortholog_one2one ) GuineaPig_ ECD ( ortholog_one2one ) Macaque_ ECD ( ortholog_one2one ) Mouse_ Ecd ( ortholog_one2one ) Pig_ ECD ( ortholog_one2one ) Rat_ Ecd ( ortholog_one2one ) Rabbit_ ECD ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in muscle and heart. Over-expressed in pancreatic and breast cancers. {ECO:0000269|PubMed:22270930, ECO:0000269|PubMed:22977192}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002569(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3812619 rs151023501 rs3736518 rs36152134 rs2271904 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16849563, ECO:0000269|PubMed:19919181, ECO:0000269|PubMed:26711270}. Nucleus {ECO:0000269|PubMed:16849563, ECO:0000269|PubMed:19919181, ECO:0000269|PubMed:26711270}. Note=Predominantly is located in the cytoplasm. {ECO:0000269|PubMed:16849563, ECO:0000269|PubMed:19919181, ECO:0000269|PubMed:26711270}. |
| Mouse PG classification | NA |
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