| Gene Information | |
|---|---|
| Gene Name | PLA2G12A |
| Organism | Homo sapiens (Human) |
| Gene Length | 189 |
| Protein Names | Group XIIA secretory phospholipase A2 (GXII sPLA2) (sPLA2-XII) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase 12A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000123739 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BZM1 |
| Gene Card | PLA2G12A |
| Uniprot ID | Q9BZM1 |
| Pfam | PF06951 |
| In ASD | no |
| Allosteric Prediction | no (-0.311782301) |
| Ortholog in Animals | Alpaca_ PLA2G12A ( ortholog_one2one ) Dog_ PLA2G12A ( ortholog_one2one ) GuineaPig_ PLA2G12A ( ortholog_one2one ) Mouse_ Pla2g12a ( ortholog_one2one ) Pig_ PLA2G12A ( ortholog_one2one ) Rat_ Pla2g12a ( ortholog_one2one ) |
| Ohnologs | PLA2G12B |
| Paralogs | PLA2G12B |
| Tissue | NA |
| Tissue Specificity | Abundantly expressed in heart, skeletal muscle, kidney, liver and pancreas. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:12522102}. Cytoplasm {ECO:0000269|PubMed:12522102}. |
| Mouse PG classification | NA |
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