| Gene Information | |
|---|---|
| Gene Name | EAP45 |
| Organism | Homo sapiens (Human) |
| Gene Length | 386 |
| Protein Names | Vacuolar protein-sorting-associated protein 36 (ELL-associated protein of 45 kDa) (ESCRT-II complex subunit VPS36) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q86VN1 |
| Gene Card | VPS36 |
| Uniprot ID | Q86VN1 |
| Pfam | PF04157; PF11605 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.045476(Chimpanzee);0.001000(Mouse);0.002240(Rat);0.072321(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2HTH (X-ray 2.70A ) 2ZME (X-ray 2.90A ) 3CUQ (X-ray 2.61A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Endosome. Late endosome {ECO:0000250|UniProtKB:Q91XD6}. Membrane. Nucleus {ECO:0000305}. Note=Colocalizes with ubiquitinated proteins on late endosomes. Recruited to the endosome membrane to participate in vesicle formation. {ECO:0000250|UniProtKB:Q91XD6}. |
| Mouse PG classification | NA |
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