Gene Information
Gene NameEAF2
OrganismHomo sapiens (Human)
Gene Length260
Protein NamesELL-associated factor 2 (Testosterone-regulated apoptosis inducer and tumor suppressor protein)
Target NameNA
Target TypeNA
Gene Age680 ( ENSG00000145088 )
Evolutionary StageEumetazoa
AlphaFoldDBQ96CJ1
Gene CardEAF2
Uniprot IDQ96CJ1
PfamPF09816
In ASDno
Allosteric Predictionno (-0.899221484)
Ortholog in AnimalsAlpaca_ EAF2 ( ortholog_one2one )
Dog_ EAF2 ( ortholog_one2one )
GuineaPig_ EAF2 ( ortholog_one2one )
Macaque_ EAF2 ( ortholog_one2one )
Mouse_ Eaf2 ( ortholog_one2one )
Pig_ EAF2 ( ortholog_one2one )
Rat_ Eaf2 ( ortholog_one2one )
Rabbit_ EAF2 ( ortholog_one2one )
OhnologsEAF1
ParalogsEAF1
TissueNA
Tissue SpecificityExpressed in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, spleen, prostate, testis, small intestine, colon, adrenal, bone marrow, lymph node, spinal gland, stomach, thyroid, trachea, thymus, liver and leukocytes. {ECO:0000269|PubMed:12446457, ECO:0000269|PubMed:12907652}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.003490(Rat);0.085714(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Nucleus speckle {ECO:0000269|PubMed:12446457, ECO:0000269|PubMed:12907652}.
Mouse PG classificationNA
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