| Gene Information | |
|---|---|
| Gene Name | EAF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 268 |
| Protein Names | ELL-associated factor 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000144597 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96JC9 |
| Gene Card | EAF1 |
| Uniprot ID | Q96JC9 |
| Pfam | PF09816 |
| In ASD | no |
| Allosteric Prediction | no (-1.202251546) |
| Ortholog in Animals | Alpaca_ EAF1 ( ortholog_one2one ) Dog_ EAF1 ( ortholog_one2one ) GuineaPig_ EAF1 ( ortholog_one2one ) Macaque_ EAF1 ( ortholog_one2one ) Mouse_ Eaf1 ( ortholog_one2one ) Pig_ EAF1 ( ortholog_one2one ) Rat_ Eaf1 ( ortholog_one2one ) Rabbit_ EAF1 ( ortholog_one2one ) |
| Ohnologs | EAF2 |
| Paralogs | EAF2 |
| Tissue | NA |
| Tissue Specificity | Strongly expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, prostate, testis, small intestine and colon. Poorly expressed in thymus. {ECO:0000269|PubMed:11418481}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001990(Rat);0.052632(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7OKX (EM 3.30A ) 7OKY (EM 4.14A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus speckle {ECO:0000269|PubMed:11418481}. Nucleus, Cajal body {ECO:0000269|PubMed:12686606}. |
| Mouse PG classification | NA |
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