| Gene Information | |
|---|---|
| Gene Name | E2F4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 413 |
| Protein Names | Transcription factor E2F4 (E2F-4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000205250 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q16254 |
| Gene Card | E2F4 |
| Uniprot ID | Q16254 |
| Pfam | PF16421; PF02319 |
| In ASD | no |
| Allosteric Prediction | no (-0.397391312) |
| Ortholog in Animals | Dog_ E2F4 ( ortholog_one2one ) GuineaPig_ E2F4 ( ortholog_one2one ) Macaque_ E2F4 ( ortholog_one2one ) Mouse_ E2f4 ( ortholog_one2one ) Pig_ E2F4 ( ortholog_one2one ) Rat_ E2f4 ( ortholog_one2one ) |
| Ohnologs | E2F5 |
| Paralogs | E2F5, E2F2, E2F6, E2F3, E2F8, E2F1, E2F7 |
| Tissue | NA |
| Tissue Specificity | Found in all tissue examined including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003931(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1CF7 (X-ray 2.60A ) 5TUU (X-ray 2.25A ) |
| DBSNP | rs1801013 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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