| Gene Information | |
|---|---|
| Gene Name | LRIT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 550 |
| Protein Names | Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2 (Leucine-rich repeat-containing protein 22) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000204033 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | A6NDA9 |
| Gene Card | LRIT2 |
| Uniprot ID | A6NDA9 |
| Pfam | PF13855 |
| In ASD | no |
| Allosteric Prediction | no (-2.097531992) |
| Ortholog in Animals | Alpaca_ LRIT2 ( ortholog_one2one ) Dog_ LRIT2 ( ortholog_one2one ) GuineaPig_ LRIT2 ( ortholog_one2one ) Macaque_ LRIT2 ( ortholog_one2one ) Mouse_ Lrit2 ( ortholog_one2one ) Pig_ LRIT2 ( ortholog_one2one ) Rat_ Lrit2 ( ortholog_one2one ) Rabbit_ LRIT2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CD180, RXFP1, TLR8, NRROS, TLR5, TSKU, TLR7, TLR10, RXFP2, TLR6, LRRC3B, IGFALS, TLR3, TLR2, TLR4, LRRC17, LRRC32, LRRC53, VASN, TLR1, LRRC3C, LRRC3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12773843 rs11200927 rs11200925 rs12217769 rs6585847 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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