| Gene Information | |
|---|---|
| Gene Name | DYNLT4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 221 |
| Protein Names | Dynein light chain Tctex-type 4 (Protein N22.1) (Tctex-2-beta) (Tctex1 domain-containing protein 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000188396 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q5JR98 |
| Gene Card | DYNLT4 |
| Uniprot ID | Q5JR98 |
| Pfam | PF03645 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | Alpaca_ DYNLT4 ( ortholog_one2one ) Dog_ DYNLT4 ( ortholog_one2one ) GuineaPig_ DYNLT4 ( ortholog_one2one ) Macaque_ DYNLT4 ( ortholog_one2one ) Mouse_ Dynlt4 ( ortholog_one2one ) Pig_ DYNLT4 ( ortholog_one2one ) Rat_ Dynlt4 ( ortholog_one2one ) Rabbit_ DYNLT4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DYNLT5, DYNLT2, DYNLT3, DYNLT2B, DYNLT1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed (PubMed:16982625). Expressed in testis (at protein level) (PubMed:23789093). {ECO:0000269|PubMed:16982625, ECO:0000269|PubMed:23789093}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell projection, cilium, flagellum {ECO:0000269|PubMed:23789093}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:23789093}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:23789093}. Cytoplasm {ECO:0000250|UniProtKB:Q8CDY7}. Nucleus {ECO:0000250|UniProtKB:Q8CDY7}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000269|PubMed:23789093}. Note=Present along the entire length of the flagellum, including principal and endpiece, and more predominantly in the midpiece region. {ECO:0000269|PubMed:23789093}. |
| Mouse PG classification | NA |
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