| Gene Information | |
|---|---|
| Gene Name | DYNLT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 198 |
| Protein Names | Dynein light chain Tctex-type protein 2 (T-complex testis-specific protein 3) (T-complex-associated testis-expressed protein 3) (Tcte-3) (Tctex1 domain-containing protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000184786 ) 3 ( ENSG00000275368 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8IZS6 |
| Gene Card | DYNLT2 |
| Uniprot ID | Q8IZS6 |
| Pfam | PF03645 |
| In ASD | no |
| Allosteric Prediction | no (-1.576498031) |
| Ortholog in Animals | Alpaca_ DYNLT2 ( ortholog_one2one ) GuineaPig_ DYNLT2 ( ortholog_one2one ) Macaque_ DYNLT2 ( ortholog_one2one ) Mouse_ Dynlt2a1 ( ortholog_one2many ) Mouse_ Dynlt2a3 ( ortholog_one2many ) Mouse_ Dynlt2a2 ( ortholog_one2many ) Pig_ DYNLT2 ( ortholog_one2one ) Rat_ Dynlt2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DYNLT4, DYNLT5, DYNLT3, DYNLT2B, DYNLT1 |
| Tissue | testis |
| Tissue Specificity | Expressed predominantly in testis. Also expressed in brain, lung and trachea. {ECO:0000269|PubMed:11278908, ECO:0000269|PubMed:12584439}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs116980543 rs2027063 rs13194101 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P11985}. Cytoplasmic granule {ECO:0000250|UniProtKB:P11985}. Membrane {ECO:0000250|UniProtKB:P11985}; Peripheral membrane protein {ECO:0000250|UniProtKB:P11985}. Note=Found on the surface of sperm tail. Stored in cytoplasmic granules during spermatogenesis. {ECO:0000250|UniProtKB:P11985}. |
| Mouse PG classification | NA |
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