| Gene Information | |
|---|---|
| Gene Name | SYT8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 401 |
| Protein Names | Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000149043 ) 3 ( ENSG00000288149 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q8NBV8 |
| Gene Card | SYT8 |
| Uniprot ID | Q8NBV8 |
| Pfam | PF00168 |
| In ASD | no |
| Allosteric Prediction | yes (0.189159465) |
| Ortholog in Animals | Alpaca_ SYT8 ( ortholog_one2one ) Dog_ SYT8 ( ortholog_one2one ) GuineaPig_ SYT8 ( ortholog_one2one ) Macaque_ SYT8 ( ortholog_one2one ) Mouse_ Syt8 ( ortholog_one2one ) Pig_ SYT8 ( ortholog_one2one ) Rat_ Syt8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SYT2, SYTL3, SYT13, TC2N, SYT1, SYT7, SYTL4, SYTL5, DOC2B, DOC2A, SYT14, C2CD4C, SYTL1, RPH3A, SYT4, SYT11, SYT12, C2CD4A, C2CD4B, RPH3AL, SYT15, SYT15B, SYT9, SYT16, SYT6, C2CD4D, SYT3, SYTL2, SYT10, SYT5, SYT17 |
| Tissue | gall.bladder, skin, urinary.bladder, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs57344881 rs564271 rs34141314 rs907608 rs907609 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250}. |
| Mouse PG classification | NA |
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