| Gene Information | |
|---|---|
| Gene Name | DYM |
| Organism | Homo sapiens (Human) |
| Gene Length | 669 |
| Protein Names | Dymeclin (Dyggve-Melchior-Clausen syndrome protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000141627 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q7RTS9 |
| Gene Card | DYM |
| Uniprot ID | Q7RTS9 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.239131771) |
| Ortholog in Animals | Alpaca_ DYM ( ortholog_one2one ) Dog_ DYM ( ortholog_one2one ) GuineaPig_ DYM ( ortholog_one2one ) Macaque_ DYM ( ortholog_one2one ) Mouse_ Dym ( ortholog_one2one ) Pig_ DYM ( ortholog_one2one ) Rat_ Dym ( ortholog_one2one ) Rabbit_ DYM ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in most embryo-fetal and adult tissues. Abundant in primary chondrocytes, osteoblasts, cerebellum, kidney, lung, stomach, heart, pancreas and fetal brain. Very low or no expression in the spleen, thymus, esophagus, bladder and thyroid gland. {ECO:0000269|PubMed:12554689, ECO:0000269|PubMed:18996921}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs120074164 rs120074163 rs120074165 |
| Subcellular location [CC] | Cytoplasm. Golgi apparatus. Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Note=Sequence analysis programs clearly predict 1 transmembrane region. However, PubMed:18996921 shows that it is not a stably anchored transmembrane protein but it weakly associates with the Golgi apparatus and shuttles between the Golgi and the cytosol. |
| Mouse PG classification | HPG |
| click here to return to the previous page | |