| Gene Information | |
|---|---|
| Gene Name | DVL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 695 |
| Protein Names | Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000107404 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O14640 |
| Gene Card | DVL1 |
| Uniprot ID | O14640 |
| Pfam | PF00610; PF02377; PF00778; PF12316; PF00595 |
| In ASD | no |
| Allosteric Prediction | no (-0.317473029) |
| Ortholog in Animals | Alpaca_ DVL1 ( ortholog_one2one ) Dog_ DVL1 ( ortholog_one2one ) GuineaPig_ DVL1 ( ortholog_one2one ) Macaque_ DVL1 ( ortholog_one2one ) Mouse_ Dvl1 ( ortholog_one2one ) Pig_ DVL1 ( ortholog_one2one ) Rat_ Dvl1 ( ortholog_one2one ) |
| Ohnologs | DVL2, DVL3 |
| Paralogs | DIXDC1, DVL2, DVL3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001942(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6LCA (X-ray 2.40A ) 6LCB (X-ray 1.40A ) 6TTK (X-ray 2.38A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Note=Localizes at the cell membrane upon interaction with frizzled family members. {ECO:0000250}. |
| Mouse PG classification | LPG |
| click here to return to the previous page | |