| Gene Information | |
|---|---|
| Gene Name | USO1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 962 |
| Protein Names | General vesicular transport factor p115 (Protein USO1 homolog) (Transcytosis-associated protein) (TAP) (Vesicle-docking protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000138768 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O60763 |
| Gene Card | USO1 |
| Uniprot ID | O60763 |
| Pfam | PF18770; PF04871; PF04869 |
| In ASD | no |
| Allosteric Prediction | no (-0.057684651) |
| Ortholog in Animals | Alpaca_ USO1 ( ortholog_one2one ) Dog_ USO1 ( ortholog_one2one ) GuineaPig_ USO1 ( ortholog_one2one ) Macaque_ USO1 ( ortholog_one2one ) Mouse_ Uso1 ( ortholog_one2one ) Pig_ USO1 ( ortholog_one2one ) Rat_ Uso1 ( ortholog_one2one ) Rabbit_ USO1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2W3C (X-ray 2.22A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:19454686, ECO:0000269|PubMed:9478999}. Golgi apparatus membrane {ECO:0000269|PubMed:19454686, ECO:0000269|PubMed:9478999}; Peripheral membrane protein {ECO:0000269|PubMed:19454686, ECO:0000269|PubMed:9478999}. Note=Recycles between the cytosol and the Golgi apparatus during interphase. During interphase, the phosphorylated form is found exclusively in cytosol; the unphosphorylated form is associated with Golgi apparatus membranes. {ECO:0000269|PubMed:19454686, ECO:0000269|PubMed:9478999}. |
| Mouse PG classification | NA |
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