| Gene Information | |
|---|---|
| Gene Name | ERLIN2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 339 |
| Protein Names | Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000147475 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O94905 |
| Gene Card | ERLIN2 |
| Uniprot ID | O94905 |
| Pfam | PF01145 |
| In ASD | no |
| Allosteric Prediction | no (-0.249215456) |
| Ortholog in Animals | Alpaca_ ERLIN2 ( ortholog_one2one ) Dog_ ERLIN2 ( ortholog_one2one ) GuineaPig_ ERLIN2 ( ortholog_one2one ) Macaque_ ERLIN2 ( ortholog_one2one ) Mouse_ Erlin2 ( ortholog_one2one ) Pig_ ERLIN2 ( ortholog_one2one ) Rat_ Erlin2 ( ortholog_one2one ) Rabbit_ ERLIN2 ( ortholog_one2one ) |
| Ohnologs | ERLIN1 |
| Paralogs | ERLIN1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:10449903}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2032066 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:16835267, ECO:0000269|PubMed:17502376, ECO:0000269|PubMed:19240031}; Single-pass type II membrane protein {ECO:0000269|PubMed:16835267, ECO:0000269|PubMed:17502376, ECO:0000269|PubMed:19240031}. Note=Associated with lipid raft-like domains of the endoplasmic reticulum membrane. |
| Mouse PG classification | LPG |
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