| Gene Information | |
|---|---|
| Gene Name | DUSP15 |
| Organism | Homo sapiens (Human) |
| Gene Length | 295 |
| Protein Names | Dual specificity protein phosphatase 15 (EC 3.1.3.16) (EC 3.1.3.48) (VH1-related member Y) (Vaccinia virus VH1-related dual-specific protein phosphatase Y) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000149599 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H1R2 |
| Gene Card | DUSP15 |
| Uniprot ID | Q9H1R2 |
| Pfam | PF00782 |
| In ASD | no |
| Allosteric Prediction | no (-0.969910813) |
| Ortholog in Animals | Alpaca_ DUSP15 ( ortholog_one2one ) Dog_ DUSP15 ( ortholog_one2one ) GuineaPig_ DUSP15 ( ortholog_one2one ) Macaque_ DUSP15 ( ortholog_one2one ) Mouse_ Dusp15 ( ortholog_one2one ) Pig_ DUSP15 ( ortholog_one2one ) Rat_ Dusp15 ( ortholog_one2one ) |
| Ohnologs | DUSP22 |
| Paralogs | DUSP6, DUSP4, DUSP12, DUSP10, STYXL2, SSH3, DUSP19, DUSP1, KASH5, SSH1, DUSP29, DUSP16, DUSP21, DUSP2, DUSP8, DUSP13, EPM2A, DUSP7, DUSP26, STYX, SSH2, PTPMT1, DUSP22, DUSP18, DUSP14, DUSP28, STYXL1, DUSP5, DUSP9, DUSP3 |
| Tissue | testis, kidney |
| Tissue Specificity | Highly expressed in testis (PubMed:15138252). Expressed in brain; up-regulated in patients with multiple sclerosis gray matter lesions (PubMed:22792334). {ECO:0000269|PubMed:15138252, ECO:0000269|PubMed:22792334}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1YZ4 (X-ray 2.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000305|PubMed:15138252}.; [Isoform 3]: Cell membrane; Lipid-anchor; Cytoplasmic side. |
| Mouse PG classification | NA |
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