| Gene Information | |
|---|---|
| Gene Name | DUS2L |
| Organism | Homo sapiens (Human) |
| Gene Length | 493 |
| Protein Names | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (EC 1.3.1.91) (Dihydrouridine synthase 2) (Up-regulated in lung cancer protein 8) (URLC8) (tRNA-dihydrouridine synthase 2-like) (hDUS2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9NX74 |
| Gene Card | DUS2 |
| Uniprot ID | Q9NX74 |
| Pfam | PF00035; PF01207 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Weak expression in heart, placenta and skeletal muscle. Up-regulated in most lung cancer cells (at protein level). {ECO:0000269|PubMed:15994936}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4WFS (X-ray 2.68A ) 4WFT (X-ray 1.70A ) 4XP7 (X-ray 1.90A ) 5OC4 (X-ray 1.71A ) 5OC5 (X-ray 1.89A ) 5OC6 (X-ray 3.20A ) 6EI8 (X-ray 2.25A ) 6EZA (X-ray 2.00A ) 6EZB (X-ray 2.25A ) 6EZC (X-ray 2.00A ) 6F00 (X-ray 2.16A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15994936}. Endoplasmic reticulum {ECO:0000269|PubMed:15994936}. Note=Mainly at the endoplasmic reticulum. {ECO:0000269|PubMed:15994936}. |
| Mouse PG classification | NA |
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