Gene Information
Gene NameDULP
OrganismHomo sapiens (Human)
Gene Length246
Protein NamesTransmembrane and ubiquitin-like domain-containing protein 1 (Dendritic cell-derived ubiquitin-like protein) (DULP) (Hepatocyte odd protein shuttling protein) (Ubiquitin-like protein SB144) [Cleaved into: iHOPS]
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9BVT8
Gene CardTMUB1
Uniprot IDQ9BVT8
PfamPF00240
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityUbiquitously expressed with highest levels in mammary and thyroid glands, bone marrow and spleen;
limited expression in cardiac, pancreatic and ovarian tissues. {ECO:0000269|PubMed:24240191}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Membrane {ECO:0000250|UniProtKB:Q9JMG3};
Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9JMG3}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q9JMG3}. Recycling endosome {ECO:0000250|UniProtKB:Q53AQ4}. Cytoplasm {ECO:0000250|UniProtKB:Q9JMG3}. Nucleus {ECO:0000250|UniProtKB:Q9JMG3}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9JMG3}.;
[iHOPS]: Cytoplasm {ECO:0000250|UniProtKB:Q53AQ4, ECO:0000250|UniProtKB:Q9JMG3}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q9JMG3}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9JMG3}. Nucleus {ECO:0000250|UniProtKB:Q9JMG3}. Note=iHOPS is proposed to be the shuttling form across different cellular compartments. XPO1-dependent exported from the nucleus in dividing cells. Predominantly nuclear during growth arrest. {ECO:0000250|UniProtKB:Q9JMG3}.
Mouse PG classificationNA
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