| Gene Information | |
|---|---|
| Gene Name | SURF4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 269 |
| Protein Names | Surfeit locus protein 4 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000148248 ) 3 ( ENSG00000280951 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | O15260 |
| Gene Card | SURF4 |
| Uniprot ID | O15260 |
| Pfam | PF02077 |
| In ASD | no |
| Allosteric Prediction | no (-0.591582045) |
| Ortholog in Animals | Alpaca_ SURF4 ( ortholog_one2one ) Dog_ SURF4 ( ortholog_one2one ) GuineaPig_ SURF4 ( ortholog_one2one ) Macaque_ SURF4 ( ortholog_one2one ) Mouse_ Surf4 ( ortholog_one2one ) Pig_ SURF4 ( ortholog_one2one ) Rat_ Surf4 ( ortholog_one2many ) Rat_ Surf1 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | SURF1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:15308636, ECO:0000269|PubMed:18287528, ECO:0000269|PubMed:30251625, ECO:0000269|PubMed:33186557}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:18287528}; Multi-pass membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000269|PubMed:18287528, ECO:0000269|PubMed:30251625, ECO:0000269|PubMed:33186557}; Multi-pass membrane protein {ECO:0000255}. Note=Cycles between the endoplasmic reticulum and the Golgi. {ECO:0000269|PubMed:18287528, ECO:0000269|PubMed:33186557}. |
| Mouse PG classification | NA |
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