| Gene Information | |
|---|---|
| Gene Name | EFL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1120 |
| Protein Names | Elongation factor-like GTPase 1 (Elongation factor Tu GTP-binding domain-containing protein 1) (Elongation factor-like 1) (Protein FAM42A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000140598 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q7Z2Z2 |
| Gene Card | EFL1 |
| Uniprot ID | Q7Z2Z2 |
| Pfam | PF00679; PF14492; PF00009 |
| In ASD | no |
| Allosteric Prediction | no (-0.471169762) |
| Ortholog in Animals | Alpaca_ EFL1 ( ortholog_one2one ) Alpaca_ EFL1 ( ortholog_one2many ) Dog_ EFL1 ( ortholog_one2one ) GuineaPig_ EFL1 ( ortholog_one2one ) Macaque_ EFL1 ( ortholog_one2one ) Mouse_ Efl1 ( ortholog_one2one ) Pig_ EFL1 ( ortholog_one2one ) Rat_ Efl1 ( ortholog_one2one ) Rabbit_ EFL1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EFTUD2, EIF2S3, EIF2S3B, GTPBP1, GUF1, EIF5B, MTIF2, EEF2, GSPT2, EEFSEC, EEF1A1, EEF1A2, HBS1L, GTPBP2, GFM2, GFM1, GSPT1, TUFM |
| Tissue | NA |
| Tissue Specificity | Expressed at low levels in brain. Expression is highly increased in glioma tissues. {ECO:0000269|PubMed:25015090}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5ANB (EM 4.10A ) 5ANC (EM 4.20A ) |
| DBSNP | rs2292189 rs1128431 rs2292071 rs1316615934 rs376095522 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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