| Gene Information | |
|---|---|
| Gene Name | DTD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 209 |
| Protein Names | D-aminoacyl-tRNA deacylase 1 (DTD) (EC 3.1.1.96) (DNA-unwinding element-binding protein B) (DUE-B) (Gly-tRNA(Ala) deacylase) (Histidyl-tRNA synthase-related) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000125821 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8TEA8 |
| Gene Card | DTD1 |
| Uniprot ID | Q8TEA8 |
| Pfam | PF02580 |
| In ASD | no |
| Allosteric Prediction | no (-1.31734853) |
| Ortholog in Animals | Alpaca_ DTD1 ( ortholog_one2one ) GuineaPig_ DTD1 ( ortholog_one2one ) Macaque_ DTD1 ( ortholog_one2many ) Mouse_ Dtd1 ( ortholog_one2one ) Pig_ DTD1 ( ortholog_one2one ) Rat_ Dtd1 ( ortholog_one2one ) Rabbit_ DTD1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DTD2 |
| Tissue | NA |
| Tissue Specificity | Expressed in many adult and fetal tissues. Highest levels in testis, ovary, spleen and in adult and fetal brain. {ECO:0000269|PubMed:12392168}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002323(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2OKV (X-ray 2.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:15653697, ECO:0000269|PubMed:20065034}. Cytoplasm {ECO:0000250|UniProtKB:Q8IIS0}. Note=Associated with chromatin at some replication origins containing functional DNA-unwinding elements (PubMed:20065034). |
| Mouse PG classification | NA |
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