| Gene Information | |
|---|---|
| Gene Name | DSC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 896 |
| Protein Names | Desmocollin-3 (Cadherin family member 3) (Desmocollin-4) (HT-CP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000134762 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q14574 |
| Gene Card | DSC3 |
| Uniprot ID | Q14574 |
| Pfam | PF01049; PF00028; PF08758 |
| In ASD | no |
| Allosteric Prediction | no (-0.713986566) |
| Ortholog in Animals | Alpaca_ DSC3 ( ortholog_one2one ) Macaque_ DSC3 ( ortholog_one2one ) Mouse_ Dsc3 ( ortholog_one2one ) Pig_ DSC3 ( ortholog_one2one ) Rat_ Dsc3 ( ortholog_one2one ) Rabbit_ DSC3 ( ortholog_one2one ) |
| Ohnologs | CDH3, CDH15, CDH13 |
| Paralogs | DSC2, DSC1, DSG1, DSG3, DSG4, DSG2 |
| Tissue | skin, tongue, zone.of.skin, esophagus.mucosa, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | Epidermis, buccal mucosa, esophagus and cervix. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2852003 rs276937 rs276938 rs35296997 rs276921 rs35630063 |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome. |
| Mouse PG classification | NA |
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