| Gene Information | |
|---|---|
| Gene Name | DSC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 252 |
| Protein Names | Calcipressin-1 (Adapt78) (Down syndrome critical region protein 1) (Myocyte-enriched calcineurin-interacting protein 1) (MCIP1) (Regulator of calcineurin 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000134765 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P53805 |
| Gene Card | RCAN1 |
| Uniprot ID | P53805 |
| Pfam | PF04847 |
| In ASD | no |
| Allosteric Prediction | no (-0.574315922) |
| Ortholog in Animals | Alpaca_ DSC1 ( ortholog_one2one ) GuineaPig_ DSC1 ( ortholog_one2one ) Macaque_ DSC1 ( ortholog_one2one ) Mouse_ Dsc1 ( ortholog_one2one ) Pig_ DSC1 ( ortholog_one2one ) Rat_ Dsc1 ( ortholog_one2one ) Rabbit_ DSC1 ( ortholog_one2one ) |
| Ohnologs | CDH3, CDH15, CDH13 |
| Paralogs | DSC2, DSC3, DSG1, DSG3, DSG4, DSG2 |
| Tissue | skin, zone.of.skin, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | Highly expressed heart, brain and skeletal muscle. Also expressed in all other tissues. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6UUQ (X-ray 1.85A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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