| Gene Information | |
|---|---|
| Gene Name | NKG7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 165 |
| Protein Names | Protein NKG7 (G-CSF-induced gene 1 protein) (GIG-1 protein) (Granule membrane protein of 17 kDa) (GMP-17) (Natural killer cell protein 7) (p15-TIA-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000105374 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q16617 |
| Gene Card | NKG7 |
| Uniprot ID | Q16617 |
| Pfam | PF00822 |
| In ASD | no |
| Allosteric Prediction | no (-0.86404507) |
| Ortholog in Animals | Alpaca_ NKG7 ( ortholog_one2one ) Dog_ NKG7 ( ortholog_one2one ) GuineaPig_ NKG7 ( ortholog_one2one ) Macaque_ NKG7 ( ortholog_one2one ) Mouse_ Nkg7 ( ortholog_one2one ) Pig_ NKG7 ( ortholog_one2one ) Rat_ Nkg7 ( ortholog_one2one ) Rabbit_ NKG7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EMP1, PMP22, EMP2, EMP3, LIM2, CLDND2, TMEM202, GSG1, GSG1L, GSG1L2 |
| Tissue | whole.blood |
| Tissue Specificity | Expressed in activated T-cells, in kidney, liver, lung and pancreas. Not expressed in brain, heart, or skeletal muscle. Expressed at high levels in TCR gamma delta-expressing CTL clones, and in some TCR alpha beta-expressing CTL clones (both CD4+ and CD8+), but is not expressed in other TCR alpha beta-expressing CTL clones and in cell lines representing B-cells, monocytes, and myeloid cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:8570616}; Multi-pass membrane protein {ECO:0000269|PubMed:8570616}. Cytolytic granule membrane {ECO:0000269|PubMed:8570616}; Multi-pass membrane protein {ECO:0000269|PubMed:8570616}. |
| Mouse PG classification | NA |
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