| Gene Information | |
|---|---|
| Gene Name | DREF |
| Organism | Homo sapiens (Human) |
| Gene Length | 694 |
| Protein Names | E3 SUMO-protein ligase ZBED1 (EC 2.3.2.-) (DNA replication-related element-binding factor) (Putative Ac-like transposable element) (Zinc finger BED domain-containing protein 1) (dREF homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O96006 |
| Gene Card | ZBED1 |
| Uniprot ID | O96006 |
| Pfam | PF05699; PF02892 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed at low levels (PubMed:9887332). Expression is highest in skeletal muscle, heart, spleen and placenta (PubMed:9887332). {ECO:0000269|PubMed:9887332}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CT5 (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus, PML body {ECO:0000269|PubMed:25210186, ECO:0000269|PubMed:27068747}. Nucleus {ECO:0000269|PubMed:12663651, ECO:0000269|PubMed:17209048}. Note=In granular structures. {ECO:0000269|PubMed:12663651, ECO:0000269|PubMed:17209048}.; Nucleus, PML body. Note=(Microbial infection) Upon interaction with human adenovirus early E1A protein, the protein is redistributed to the peripheral areas of PML bodies. {ECO:0000269|PubMed:25210186}. |
| Mouse PG classification | NA |
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