| Gene Information | |
|---|---|
| Gene Name | CIC |
| Organism | Homo sapiens (Human) |
| Gene Length | 1608 |
| Protein Names | Protein capicua homolog |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000079432 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96RK0 |
| Gene Card | CIC |
| Uniprot ID | Q96RK0 |
| Pfam | PF00505 |
| In ASD | no |
| Allosteric Prediction | no (-0.695047637) |
| Ortholog in Animals | Alpaca_ CIC ( ortholog_one2one ) Dog_ CIC ( ortholog_one2one ) GuineaPig_ CIC ( ortholog_one2one ) Macaque_ CIC ( ortholog_one2one ) Mouse_ Cic ( ortholog_one2one ) Pig_ CIC ( ortholog_one2one ) Rat_ Cic ( ortholog_one2one ) Rabbit_ CIC ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | BBX |
| Tissue | NA |
| Tissue Specificity | Expressed in fetal brain. {ECO:0000269|PubMed:15981098}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.2(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2M41 (NMR - ) 4J2J (X-ray 2.50A ) 4J2L (X-ray 3.15A ) 6JRP (X-ray 3.00A ) 6KZG (X-ray 2.00A ) 6KZH (X-ray 2.65A ) |
| DBSNP | rs373584239 rs770323488 rs17339472 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}. |
| Mouse PG classification | NA |
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