| Gene Information | |
|---|---|
| Gene Name | BAIAP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1491 |
| Protein Names | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Trinucleotide repeat-containing gene 19 protein) (WW domain-containing protein 3) (WWP3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96QZ7 |
| Gene Card | MAGI1 |
| Uniprot ID | Q96QZ7 |
| Pfam | PF00625; PF00595; PF00397 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed with the exception of skeletal muscle. Isoform 1, isoform 2 and isoform 6 are highly expressed in colon, kidney, lung, liver, and pancreas. Isoform 5 is predominantly expressed in brain and heart. Isoform 3 and isoform 4 are highly expressed in pancreas and brain. {ECO:0000269|PubMed:11969287, ECO:0000269|PubMed:9647693, ECO:0000269|PubMed:9647739}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WBP (X-ray 2.40A ) 2KPK (NMR - ) 2KPL (NMR - ) 2Q9V (X-ray 2.00A ) 2R4H (X-ray 2.05A ) 2YSD (NMR - ) 2YSE (NMR - ) 2ZAJ (NMR - ) 3BPU (X-ray 1.60A ) 5N7D (X-ray 2.30A ) 5N7F (X-ray 2.30A ) 5N7G (X-ray 2.95A ) 6TWU (X-ray 2.40A ) 6TWX (X-ray 2.30A ) 6TWY (X-ray 2.30A ) 7P71 (X-ray 2.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell junction, tight junction {ECO:0000269|PubMed:11969287}. Cell membrane {ECO:0000269|PubMed:11969287}; Peripheral membrane protein {ECO:0000269|PubMed:11969287}. Note=Localizes to epithelial cells tight junctions. |
| Mouse PG classification | NA |
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