| Gene Information | |
|---|---|
| Gene Name | DIP2B |
| Organism | Homo sapiens (Human) |
| Gene Length | 1576 |
| Protein Names | Disco-interacting protein 2 homolog B (DIP2 homolog B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000066084 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9P265 |
| Gene Card | DIP2B |
| Uniprot ID | Q9P265 |
| Pfam | PF00501; PF06464 |
| In ASD | no |
| Allosteric Prediction | no (-1.221794701) |
| Ortholog in Animals | Alpaca_ DIP2B ( ortholog_one2one ) Dog_ DIP2B ( ortholog_one2one ) GuineaPig_ DIP2B ( ortholog_one2one ) Macaque_ DIP2B ( ortholog_one2one ) Mouse_ Dip2b ( ortholog_one2one ) Pig_ DIP2B ( ortholog_one2one ) Rat_ Dip2b ( ortholog_one2one ) Rabbit_ DIP2B ( ortholog_one2one ) |
| Ohnologs | DIP2A, DIP2C |
| Paralogs | DIP2A, DIP2C |
| Tissue | NA |
| Tissue Specificity | Moderately expressed in adult brain, placenta, skeletal muscle, heart, kidney, pancreas, lung, spleen and colon. Expression was weaker in adult liver, kidney, spleen, and ovary, and in fetal brain and liver. In the brain, it is expressed in the cerebral cortex; the frontal, parietal, occipital and temporal lobes; the paracentral gyrus; the pons; the corpus callosum and the hippocampus. Highest expression levels in the brain were found in the cerebral cortex and the frontal and parietal lobes. {ECO:0000269|PubMed:10819331, ECO:0000269|PubMed:17236128}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11169525 |
| Subcellular location [CC] | Cell projection, dendrite {ECO:0000250|UniProtKB:Q3UH60}. Cell projection, axon {ECO:0000250|UniProtKB:Q3UH60}. Perikaryon {ECO:0000250|UniProtKB:Q3UH60}. |
| Mouse PG classification | NA |
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