| Gene Information | |
|---|---|
| Gene Name | POU2F1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 743 |
| Protein Names | POU domain, class 2, transcription factor 1 (NF-A1) (Octamer-binding protein 1) (Oct-1) (Octamer-binding transcription factor 1) (OTF-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000143190 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P14859 |
| Gene Card | POU2F1 |
| Uniprot ID | P14859 |
| Pfam | PF00046; PF00157; PF19536 |
| In ASD | no |
| Allosteric Prediction | no (-0.184588916) |
| Ortholog in Animals | Alpaca_ POU2F1 ( ortholog_one2one ) Dog_ POU2F1 ( ortholog_one2one ) GuineaPig_ POU2F1 ( ortholog_one2one ) Macaque_ POU2F1 ( ortholog_one2one ) Mouse_ Pou2f1 ( ortholog_one2one ) Pig_ POU2F1 ( ortholog_one2one ) Rat_ Pou2f1 ( ortholog_one2one ) Rabbit_ POU2F1 ( ortholog_one2one ) |
| Ohnologs | POU2F2 |
| Paralogs | POU1F1, POU2F3, POU4F3, POU3F3, POU6F1, POU4F1, CCDC160, HDX, POU5F1B, POU5F1, POU3F1, POU5F2, POU4F2, POU6F2, POU2F2, POU3F2, POU3F4 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Isoform 2 is lymphocyte-specific. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002101(Rat);0.010526(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1CQT (X-ray 3.20A ) 1E3O (X-ray 1.90A ) 1GT0 (X-ray 2.60A ) 1HF0 (X-ray 2.70A ) 1O4X (NMR - ) 1OCT (X-ray 3.00A ) 1POG (NMR - ) 1POU (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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