| Gene Information | |
|---|---|
| Gene Name | DPYS |
| Organism | Homo sapiens (Human) |
| Gene Length | 519 |
| Protein Names | Dihydropyrimidinase (DHP) (DHPase) (EC 3.5.2.2) (Dihydropyrimidine amidohydrolase) (Hydantoinase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000147647 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q14117 |
| Gene Card | DPYS |
| Uniprot ID | Q14117 |
| Pfam | PF01979 |
| In ASD | no |
| Allosteric Prediction | yes (0.437431417) |
| Ortholog in Animals | Alpaca_ DPYS ( ortholog_one2one ) Dog_ DPYS ( ortholog_one2one ) GuineaPig_ DPYS ( ortholog_one2one ) Macaque_ DPYS ( ortholog_one2one ) Mouse_ Dpys ( ortholog_one2one ) Pig_ DPYS ( ortholog_one2one ) Rat_ Dpys ( ortholog_one2one ) Rabbit_ DPYS ( ortholog_one2one ) |
| Ohnologs | DPYSL2, DPYSL3, DPYSL5 |
| Paralogs | DPYSL5, DPYSL3, DPYSL2, DPYSL4, CRMP1 |
| Tissue | kidney, liver |
| Tissue Specificity | Liver and kidney. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2VR2 (X-ray 2.80A ) |
| DBSNP | rs121964923 rs121964924 rs267606773 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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