| Gene Information | |
|---|---|
| Gene Name | DPH2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 489 |
| Protein Names | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (Diphthamide biosynthesis protein 2) (Diphtheria toxin resistance protein 2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000132768 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q9BQC3 |
| Gene Card | DPH2 |
| Uniprot ID | Q9BQC3 |
| Pfam | PF01866 |
| In ASD | no |
| Allosteric Prediction | no (-0.848554693) |
| Ortholog in Animals | Alpaca_ DPH2 ( ortholog_one2one ) Dog_ DPH2 ( ortholog_one2one ) GuineaPig_ DPH2 ( ortholog_one2one ) Macaque_ DPH2 ( ortholog_one2one ) Mouse_ Dph2 ( ortholog_one2one ) Pig_ DPH2 ( ortholog_one2one ) Rat_ Dph2 ( ortholog_one2one ) Rabbit_ DPH2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DPH1 |
| Tissue | NA |
| Tissue Specificity | Strongly expressed in skeletal muscle. Moderately expressed in heart, small intestine, liver, pancreas, testis and colon. Weakly expressed in brain, placenta, kidney, spleen, thymus, prostate, ovary and lymphocytes. {ECO:0000269|PubMed:9782084}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs767455462 rs755058688 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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