| Gene Information | |
|---|---|
| Gene Name | DP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 189 |
| Protein Names | Receptor expression-enhancing protein 5 (Polyposis locus protein 1) (Protein TB2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q00765 |
| Gene Card | REEP5 |
| Uniprot ID | Q00765 |
| Pfam | PF03134 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in heart (at protein level) (PubMed:32075961). Expressed in circumvallate papillae and testis (PubMed:16720576). {ECO:0000269|PubMed:16720576, ECO:0000269|PubMed:32075961}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:23969831}; Multi-pass membrane protein {ECO:0000255}. Sarcoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q60870}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes to endoplasmic reticulum tubular network (PubMed:23969831). In cardiomyocytes, localizes to the junctional sarcoplasmic reticulum membrane which is closely tethered to the cell membrane and contractile machinery (By similarity). {ECO:0000250|UniProtKB:Q60870, ECO:0000269|PubMed:23969831}. |
| Mouse PG classification | NA |
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