Gene Information
Gene NameDP1
OrganismHomo sapiens (Human)
Gene Length410
Protein NamesTranscription factor Dp-1 (DRTF1-polypeptide 1) (DRTF1) (E2F dimerization partner 1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ14186
Gene CardTFDP1
Uniprot IDQ14186
PfamPF08781; PF02319
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityHighest levels in muscle. Also expressed in brain, placenta, liver and kidney. Lower levels in lung and pancreas. Not detected in heart.
Pharmacological Animal ModelsNULL(Chimpanzee);0.069500(Mouse);0.005185(Rat);0.051915(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2AZE  (X-ray  2.55A  5GOW  (NMR  5TUU  (X-ray  2.25A  5TUV  (X-ray  2.90A 
DBSNP rs4150823 
Subcellular location [CC]Nucleus {ECO:0000250|UniProtKB:Q08639}. Cytoplasm {ECO:0000250|UniProtKB:Q08639}. Note=Shuttles between the cytoplasm and nucleus and translocates into the nuclear compartment upon heterodimerization with E2F1. {ECO:0000250|UniProtKB:Q08639}.
Mouse PG classificationNA
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