| Gene Information | |
|---|---|
| Gene Name | EXOSC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 275 |
| Protein Names | Exosome complex component RRP40 (Exosome component 3) (Ribosomal RNA-processing protein 40) (p10) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000107371 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q9NQT5 |
| Gene Card | EXOSC3 |
| Uniprot ID | Q9NQT5 |
| Pfam | PF15985 |
| In ASD | no |
| Allosteric Prediction | no (-1.058992492) |
| Ortholog in Animals | Alpaca_ EXOSC3 ( ortholog_one2one ) Dog_ EXOSC3 ( ortholog_one2one ) GuineaPig_ EXOSC3 ( ortholog_one2one ) Macaque_ EXOSC3 ( ortholog_one2one ) Mouse_ Exosc3 ( ortholog_one2one ) Pig_ EXOSC3 ( ortholog_one2one ) Rat_ Exosc3 ( ortholog_one2one ) Rabbit_ EXOSC3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EXOSC2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.073609(Rat);0.060554(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2NN6 (X-ray 3.35A ) 6D6Q (EM 3.45A ) 6D6R (EM 3.45A ) 6H25 (EM 3.80A ) |
| DBSNP | rs387907196 rs374550999 rs141138948 rs387907195 rs3208406 rs672601332 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17545563}. Nucleus, nucleolus {ECO:0000269|PubMed:20531389}. Nucleus {ECO:0000269|PubMed:17545563}. |
| Mouse PG classification | LPG |
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