| Gene Information | |
|---|---|
| Gene Name | DNTT |
| Organism | Homo sapiens (Human) |
| Gene Length | 509 |
| Protein Names | DNA nucleotidylexotransferase (EC 2.7.7.31) (Terminal addition enzyme) (Terminal deoxynucleotidyltransferase) (Terminal transferase) |
| Target Name | dna nucleotidylexotransferase |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000107447 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P04053 |
| Gene Card | DNTT |
| Uniprot ID | P04053 |
| Pfam | PF00533; PF14792; PF14791; PF10391; PF14716 |
| In ASD | no |
| Allosteric Prediction | yes (0.213692963) |
| Ortholog in Animals | Alpaca_ DNTT ( ortholog_one2one ) Dog_ DNTT ( ortholog_one2one ) GuineaPig_ DNTT ( ortholog_one2one ) Macaque_ DNTT ( ortholog_one2one ) Mouse_ Dntt ( ortholog_one2one ) Pig_ DNTT ( ortholog_one2one ) Rat_ Dntt ( ortholog_one2one ) Rabbit_ DNTT ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | POLB, POLM, POLL |
| Tissue | bone.marrow |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.087880(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2COE (NMR - ) 5W4E (X-ray 2.18A ) |
| DBSNP | rs6584066 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16371131}. |
| Mouse PG classification | NA |
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