Gene Information
Gene NameDNL2
OrganismHomo sapiens (Human)
Gene Length360
Protein NamesDeoxyribonuclease-2-alpha (EC 3.1.22.1) (Acid DNase) (Deoxyribonuclease II alpha) (DNase II alpha) (Lysosomal DNase II) (R31240_2)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBO00115
Gene CardDNASE2
Uniprot IDO00115
PfamPF03265
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in monocytes/macrophages (at protein level). {ECO:0000269|PubMed:29259162}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs36075196  rs201030953  rs16978744  rs1061192 
Subcellular location [CC]Lysosome.
Mouse PG classificationNA
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