| Gene Information | |
|---|---|
| Gene Name | LAMB3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1172 |
| Protein Names | Laminin subunit beta-3 (Epiligrin subunit bata) (Kalinin B1 chain) (Kalinin subunit beta) (Laminin B1k chain) (Laminin-5 subunit beta) (Nicein subunit beta) |
| Target Name | laminin beta-3 chain |
| Target Type | Clinical trial target |
| Gene Age | 544 ( ENSG00000196878 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q13751 |
| Gene Card | LAMB3 |
| Uniprot ID | Q13751 |
| Pfam | PF00053; PF00055 |
| In ASD | no |
| Allosteric Prediction | no (-0.483057061) |
| Ortholog in Animals | Alpaca_ LAMB3 ( ortholog_one2one ) Dog_ LAMB3 ( ortholog_one2one ) GuineaPig_ LAMB3 ( ortholog_one2one ) Macaque_ LAMB3 ( ortholog_one2one ) Mouse_ Lamb3 ( ortholog_one2one ) Pig_ LAMB3 ( ortholog_one2one ) Rat_ Lamb3 ( ortholog_one2one ) Rabbit_ LAMB3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LAMB2, LAMC3, NTN4, LAMB1, LAMA3, LAMC1, ATRNL1, LAMA2, TMEFF2, ATRN, NTN1, NTN3, LAMC2, TMEFF1, LAMA1, AGRN, LAMB4, NTNG2, NTNG1, LAMA4, MEGF9, MEGF8, EGFLAM, LAMA5, NTN5, USH2A, HSPG2 |
| Tissue | adrenal.gland, small.intestine |
| Tissue Specificity | Found in the basement membranes (major component). |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2235542 rs121912486 rs121912487 rs121912482 rs12091253 rs2229468 rs200895463 rs2076349 rs201223111 rs2229466 rs12748250 rs2076222 rs2229467 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix, basement membrane. |
| Mouse PG classification | HPG |
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