| Gene Information | |
|---|---|
| Gene Name | DNHD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 4753 |
| Protein Names | Dynein heavy chain domain-containing protein 1 (Coiled-coil domain-containing protein 35) (Dynein heavy chain domain 1-like protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000179532 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | NA |
| Gene Card | DNHD1 |
| Uniprot ID | Q96M86 |
| Pfam | PF12774; PF12780; PF08393; PF17852; PF18199; PF03028; PF12777 |
| In ASD | no |
| Allosteric Prediction | no (-1.301242529) |
| Ortholog in Animals | Alpaca_ DNHD1 ( ortholog_one2one ) GuineaPig_ DNHD1 ( ortholog_one2one ) Macaque_ DNHD1 ( ortholog_one2one ) Mouse_ Dnhd1 ( ortholog_one2one ) Rat_ Dnhd1 ( ortholog_one2one ) Rabbit_ DNHD1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DNAH3, DNAH14, DNAH9, DYNC1H1, DNAH12, DNAH2, DNAH17, DYNC2H1, DNAH7, DNAH10, DNAH6, DNAH1, DNAH5, DNAH8, DNAH11 |
| Tissue | testis |
| Tissue Specificity | Expressed in spermatozoa (at protein level). {ECO:0000269|PubMed:34932939}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2555158 rs11605196 rs369544858 rs2555152 rs11040904 rs4758423 rs11603869 rs12574381 rs1035842147 rs16915277 rs11825154 rs199752008 rs187626415 rs764070280 rs10769699 rs11604362 rs185616789 |
| Subcellular location [CC] | Cell projection, cilium, flagellum {ECO:0000269|PubMed:34932939}. Note=Predominantly concentrated in the mid-piece of the sperm flagella. {ECO:0000269|PubMed:34932939}. |
| Mouse PG classification | NA |
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