| Gene Information | |
|---|---|
| Gene Name | DNASE1L1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 302 |
| Protein Names | Deoxyribonuclease-1-like 1 (EC 3.1.21.-) (DNase X) (Deoxyribonuclease I-like 1) (DNase I-like 1) (Muscle-specific DNase I-like) (XIB) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000013563 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P49184 |
| Gene Card | DNASE1L1 |
| Uniprot ID | P49184 |
| Pfam | PF03372 |
| In ASD | no |
| Allosteric Prediction | no (-0.435607706) |
| Ortholog in Animals | Alpaca_ DNASE1L1 ( ortholog_one2one ) Dog_ DNASE1L1 ( ortholog_one2one ) GuineaPig_ DNASE1L1 ( ortholog_one2one ) Macaque_ DNASE1L1 ( ortholog_one2one ) Mouse_ Dnase1l1 ( ortholog_one2one ) Pig_ DNASE1L1 ( ortholog_one2one ) Rat_ Dnase1l1 ( ortholog_one2one ) Rabbit_ DNASE1L1 ( ortholog_one2one ) |
| Ohnologs | DNASE1L3 |
| Paralogs | DNASE1L3, DNASE1, DNASE1L2 |
| Tissue | NA |
| Tissue Specificity | Highest levels in skeletal and cardiac muscles. Detectable in all other tissues tested except brain. {ECO:0000269|PubMed:8541839}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34952165 |
| Subcellular location [CC] | Endoplasmic reticulum {ECO:0000269|PubMed:16107205}. |
| Mouse PG classification | NA |
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