| Gene Information | |
|---|---|
| Gene Name | RGS19 |
| Organism | Homo sapiens (Human) |
| Gene Length | 217 |
| Protein Names | Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000171700 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P49795 |
| Gene Card | RGS19 |
| Uniprot ID | P49795 |
| Pfam | PF00615 |
| In ASD | no |
| Allosteric Prediction | yes (0.033328238) |
| Ortholog in Animals | Alpaca_ RGS19 ( ortholog_one2one ) Dog_ RGS19 ( ortholog_one2one ) GuineaPig_ RGS19 ( ortholog_one2one ) Macaque_ RGS19 ( ortholog_one2one ) Mouse_ Rgs19 ( ortholog_one2one ) Pig_ RGS19 ( ortholog_one2one ) Rat_ Rgs19 ( ortholog_one2one ) |
| Ohnologs | RGS17, RGS20 |
| Paralogs | RGS18, RGS5, RGS3, RGS20, RGS2, RGSL1, RGS12, RGS21, AXIN1, RGS1, RGS11, RGS17, RGS7, RGS14, AXIN2, RGS22, RGS4, RGS6, RGS9, RGS13, RGS8, RGS16, RGS10 |
| Tissue | NA |
| Tissue Specificity | Highest expression in lung. Placenta, liver and heart also express high levels of GAIP. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1CMZ (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Membrane; Lipid-anchor. |
| Mouse PG classification | NA |
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