| Gene Information | |
|---|---|
| Gene Name | DNAJC6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 913 |
| Protein Names | Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000116675 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75061 |
| Gene Card | DNAJC6 |
| Uniprot ID | O75061 |
| Pfam | PF00226; PF10409 |
| In ASD | no |
| Allosteric Prediction | no (-0.022762905) |
| Ortholog in Animals | Alpaca_ DNAJC6 ( ortholog_one2one ) Dog_ DNAJC6 ( ortholog_one2one ) GuineaPig_ DNAJC6 ( ortholog_one2one ) Macaque_ DNAJC6 ( ortholog_one2one ) Mouse_ Dnajc6 ( ortholog_one2one ) Pig_ DNAJC6 ( ortholog_one2one ) Rat_ Dnajc6 ( ortholog_one2one ) Rabbit_ DNAJC6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GAK |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | Expressed in various brain regions, including cerebellum, corpus callosum, cortex, striatum, brainstem, pons, putamen, spinal cord and substantia nigra. Very low expression in non-neural tissues such as leukocytes, liver, adipose tissue, skeletal muscle and bone marrow. {ECO:0000269|PubMed:23211418}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.022222(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs61757223 rs145329294 rs770127313 rs4915691 rs879255630 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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