| Gene Information | |
|---|---|
| Gene Name | PEX7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 323 |
| Protein Names | Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000112357 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O00628 |
| Gene Card | PEX7 |
| Uniprot ID | O00628 |
| Pfam | PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-0.44576891) |
| Ortholog in Animals | Alpaca_ PEX7 ( ortholog_one2one ) Dog_ PEX7 ( ortholog_one2one ) GuineaPig_ PEX7 ( ortholog_one2one ) Macaque_ PEX7 ( ortholog_one2one ) Mouse_ Pex7 ( ortholog_one2one ) Pig_ PEX7 ( ortholog_one2one ) Rat_ Pex7 ( ortholog_one2one ) Rabbit_ PEX7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GRWD1, RBBP4, GEMIN5, WDR59, ERCC8, WDR77, RBBP7, WDR73, WDR24 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous (PubMed:9090381). Highest expression in pancreas, skeletal muscle and heart (PubMed:9090381). {ECO:0000269|PubMed:9090381}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001731(Rat);0.070599(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs61753233 rs121909152 rs121909151 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:11931631, ECO:0000269|PubMed:25538232}. Peroxisome matrix {ECO:0000269|PubMed:11546814, ECO:0000269|PubMed:11931631, ECO:0000269|PubMed:25538232}. Note=Translocated into the peroxisome matrix together with PTS2-containing cargo proteins and PEX5. {ECO:0000269|PubMed:25538232}. |
| Mouse PG classification | LPG |
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