| Gene Information | |
|---|---|
| Gene Name | ENTPD3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 529 |
| Protein Names | Ectonucleoside triphosphate diphosphohydrolase 3 (NTPDase 3) (EC 3.6.1.5) (CD39 antigen-like 3) (Ecto-ATP diphosphohydrolase 3) (Ecto-ATPDase 3) (Ecto-ATPase 3) (Ecto-apyrase 3) (HB6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000168032 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75355 |
| Gene Card | ENTPD3 |
| Uniprot ID | O75355 |
| Pfam | PF01150 |
| In ASD | no |
| Allosteric Prediction | yes (0.204289636) |
| Ortholog in Animals | Alpaca_ ENTPD3 ( ortholog_one2one ) Dog_ ENTPD3 ( ortholog_one2one ) GuineaPig_ ENTPD3 ( ortholog_one2one ) Macaque_ ENTPD3 ( ortholog_one2one ) Mouse_ Entpd3 ( ortholog_one2one ) Pig_ ENTPD3 ( ortholog_one2one ) Rat_ Entpd3 ( ortholog_one2one ) Rabbit_ ENTPD3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ENTPD8, ENTPD1, ENTPD2, ENTPD5, ENTPD6, ENTPD4, ENTPD7 |
| Tissue | NA |
| Tissue Specificity | Expressed in adult brain, pancreas, spleen and prostate (PubMed:9676430). Moderate or low expression is seen in most tissues (PubMed:9676430). Not expressed in liver and peripheral blood leukocytes (PubMed:9676430). {ECO:0000269|PubMed:9676430}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17852714 rs34266806 rs4470483 rs1047855 rs3733167 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q8BFW6}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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