| Gene Information | |
|---|---|
| Gene Name | HYOU1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 999 |
| Protein Names | Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000149428 ) 3 ( ENSG00000280682 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y4L1 |
| Gene Card | HYOU1 |
| Uniprot ID | Q9Y4L1 |
| Pfam | PF00012 |
| In ASD | no |
| Allosteric Prediction | yes (0.299145211) |
| Ortholog in Animals | Alpaca_ HYOU1 ( ortholog_one2one ) Dog_ HYOU1 ( ortholog_one2one ) GuineaPig_ HYOU1 ( ortholog_one2one ) Macaque_ HYOU1 ( ortholog_one2one ) Mouse_ Hyou1 ( ortholog_one2one ) Pig_ HYOU1 ( ortholog_one2one ) Rat_ Hyou1 ( ortholog_one2one ) Rabbit_ HYOU1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HSPA4L, HSPA6, HSPA1L, HSPH1, HSPA2, HSPA1A, HSPA1B, HSPA9, HSPA13, HSPA5, HSPA14, HSPA8, HSPA4 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in tissues that contain well-developed endoplasmic reticulum and synthesize large amounts of secretory proteins. Highly expressed in liver and pancreas and lower expression in brain and kidney. Also expressed in macrophages within aortic atherosclerotic plaques, and in breast cancers. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003212(Rat);0.02(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum lumen. |
| Mouse PG classification | NA |
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