Gene Information
Gene NameUNC5CL
OrganismHomo sapiens (Human)
Gene Length518
Protein NamesUNC5C-like protein (Protein unc-5 homolog C-like) (ZU5 and death domain-containing protein)
Target NameNA
Target TypeNA
Gene Age168 ( ENSG00000124602 )
Evolutionary StageEumetazoa
AlphaFoldDBQ8IV45
Gene CardUNC5CL
Uniprot IDQ8IV45
PfamPF00531; PF17217; PF00791
In ASDno
Allosteric Predictionno (-1.397506732)
Ortholog in AnimalsAlpaca_ UNC5CL ( ortholog_one2one )
Dog_ UNC5CL ( ortholog_one2one )
GuineaPig_ UNC5CL ( ortholog_one2one )
Macaque_ UNC5CL ( ortholog_one2one )
Mouse_ Unc5cl ( ortholog_one2one )
Pig_ UNC5CL ( ortholog_one2one )
Rat_ Unc5cl ( ortholog_one2one )
Rabbit_ UNC5CL ( ortholog_one2one )
OhnologsNA
ParalogsUNC5B, UNC5C, UNC5A, UNC5D
Tissueduodenum, gall.bladder, kidney, small.intestine, stomach, cortex.of.kidney, liver, pancreas, small.intestine.Peyers.patch
Tissue SpecificityExpressed in pancreas, liver and kidney. {ECO:0000269|PubMed:14769797}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs742493 
Subcellular location [CC]Membrane {ECO:0000305};
Single-pass type III membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:14769797}.
Mouse PG classificationNA
click here to return to the previous page