| Gene Information | |
|---|---|
| Gene Name | CFAP70 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1121 |
| Protein Names | Cilia- and flagella-associated protein 70 (Tetratricopeptide repeat protein 18) (TPR repeat protein 18) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000156042 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q5T0N1 |
| Gene Card | CFAP70 |
| Uniprot ID | Q5T0N1 |
| Pfam | PF13181 |
| In ASD | no |
| Allosteric Prediction | no (-2.038284195) |
| Ortholog in Animals | Alpaca_ CFAP70 ( ortholog_one2one ) Dog_ CFAP70 ( ortholog_one2one ) GuineaPig_ CFAP70 ( ortholog_one2one ) Macaque_ CFAP70 ( ortholog_one2one ) Mouse_ Cfap70 ( ortholog_one2one ) Pig_ CFAP70 ( ortholog_one2one ) Rat_ Cfap70 ( ortholog_one2one ) Rabbit_ CFAP70 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | BBS4, OGT, TTC34, TTC6, TMTC1, TTC16, TMTC4, TTC13, TTC7A, TMTC2, TMTC3, TTC8, IFT88, TTC7B |
| Tissue | oviduct, testis |
| Tissue Specificity | Expressed in testis. {ECO:0000269|PubMed:31621862}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12256262 rs4294502 |
| Subcellular location [CC] | Cell projection, cilium, flagellum {ECO:0000269|PubMed:31621862}. Cytoplasm, cytoskeleton, flagellum basal body {ECO:0000269|PubMed:31621862}. Cell projection, cilium {ECO:0000250|UniProtKB:D3YVL2}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:D3YVL2}. Note=Present all along the flagellum, with a marked signal at the base of the flagellum. {ECO:0000269|PubMed:31621862}. |
| Mouse PG classification | NA |
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