| Gene Information | |
|---|---|
| Gene Name | DNAJB12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 375 |
| Protein Names | DnaJ homolog subfamily B member 12 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000148719 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9NXW2 |
| Gene Card | DNAJB12 |
| Uniprot ID | Q9NXW2 |
| Pfam | PF00226; PF09320 |
| In ASD | no |
| Allosteric Prediction | no (-0.484103241) |
| Ortholog in Animals | Alpaca_ DNAJB12 ( ortholog_one2one ) Dog_ DNAJB12 ( ortholog_one2one ) GuineaPig_ DNAJB12 ( ortholog_one2one ) Macaque_ DNAJB12 ( ortholog_one2one ) Mouse_ Dnajb12 ( ortholog_one2one ) Pig_ DNAJB12 ( ortholog_one2one ) Rat_ Dnajb12 ( ortholog_one2one ) Rabbit_ DNAJB12 ( ortholog_one2one ) |
| Ohnologs | DNAJB14, DNAJC18 |
| Paralogs | DNAJB9, DNAJB14, DNAJB6, DNAJB7, DNAJB2, DNAJB13, DNAJB4, DNAJB1, DNAJB8, DNAJB5, DNAJB11 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CTP (NMR - ) |
| DBSNP | rs3750784 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:21148293, ECO:0000269|PubMed:21150129, ECO:0000269|PubMed:24732912, ECO:0000269|PubMed:27916661}; Single-pass membrane protein {ECO:0000255}. Nucleus membrane {ECO:0000269|PubMed:24732912}; Single-pass membrane protein {ECO:0000305}. Note=Localizes to the endoplasmic reticulum membrane (PubMed:21150129, PubMed:21148293, PubMed:24732912, PubMed:27916661). When overexpressed, forms membranous structures in the nucleus (PubMed:24732912). {ECO:0000269|PubMed:21148293, ECO:0000269|PubMed:21150129, ECO:0000269|PubMed:24732912, ECO:0000269|PubMed:27916661}. |
| Mouse PG classification | NA |
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