| Gene Information | |
|---|---|
| Gene Name | DNAH10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 4471 |
| Protein Names | Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000197653 ) 3 ( ENSG00000281935 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | NA |
| Gene Card | DNAH10 |
| Uniprot ID | Q8IVF4 |
| Pfam | PF12774; PF12780; PF12781; PF17857; PF18198; PF08385; PF08393; PF17852; PF18199; PF03028; PF12777 |
| In ASD | no |
| Allosteric Prediction | no (-1.249445614) |
| Ortholog in Animals | Alpaca_ DNAH10 ( ortholog_one2one ) Dog_ DNAH10 ( ortholog_one2one ) GuineaPig_ DNAH10 ( ortholog_one2one ) Macaque_ DNAH10 ( ortholog_one2one ) Mouse_ Dnah10 ( ortholog_one2one ) Pig_ DNAH10 ( ortholog_one2one ) Rat_ Tctn2 ( ortholog_one2one ) |
| Ohnologs | DNAH3, DNAH7 |
| Paralogs | DNAH3, DNHD1, DNAH14, DNAH9, DYNC1H1, DNAH12, DNAH2, DNAH17, DYNC2H1, DNAH7, DNAH6, DNAH1, DNAH5, DNAH8, DNAH11 |
| Tissue | NA |
| Tissue Specificity | Expressed primarily in trachea and testis, 2 tissues containing axonemal structures. Also expressed in brain but not in adult heart. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11057353 rs10846559 rs34934281 rs7969937 rs35685787 rs369904884 rs33935373 rs7977449 rs11835416 rs764317091 rs755346965 rs759073156 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000305}. |
| Mouse PG classification | NA |
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