| Gene Information | |
|---|---|
| Gene Name | UBE2Z |
| Organism | Homo sapiens (Human) |
| Gene Length | 354 |
| Protein Names | Ubiquitin-conjugating enzyme E2 Z (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Z) (Uba6-specific E2 conjugating enzyme 1) (Use1) (Ubiquitin carrier protein Z) (Ubiquitin-protein ligase Z) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000159202 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H832 |
| Gene Card | UBE2Z |
| Uniprot ID | Q9H832 |
| Pfam | PF00179 |
| In ASD | no |
| Allosteric Prediction | no (-0.766432111) |
| Ortholog in Animals | Alpaca_ UBE2Z ( ortholog_one2one ) Dog_ UBE2Z ( ortholog_one2one ) GuineaPig_ UBE2Z ( ortholog_one2one ) Macaque_ UBE2Z ( ortholog_one2one ) Mouse_ Ube2z ( ortholog_one2one ) Pig_ UBE2Z ( ortholog_one2one ) Rat_ Ube2z ( ortholog_one2one ) Rabbit_ UBE2Z ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | UBE2T, UBE2B, UBE2O, UBE2J2, UBE2A, UBE2C, UBE2H, UBE2V1, UBE2K, UBE2W, UBE2F, UBE2G2, UBE2I, UBE2V2, UBE2N, UBE2NL, PEDS1, UBE2U, UBE2J1, UBE2G1, UBE2S, CDC34, UBE2R2, AKTIP |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Highly in placenta, pancreas, spleen and testis. {ECO:0000269|PubMed:17160626, ECO:0000269|PubMed:17597759}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002419(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5A4P (X-ray 2.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17160626}. Nucleus {ECO:0000269|PubMed:17160626}. |
| Mouse PG classification | NA |
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