| Gene Information | |
|---|---|
| Gene Name | PRDM11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 511 |
| Protein Names | PR domain-containing protein 11 (EC 2.1.1.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000019485 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NQV5 |
| Gene Card | PRDM11 |
| Uniprot ID | Q9NQV5 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.677267299) |
| Ortholog in Animals | Alpaca_ PRDM11 ( ortholog_one2one ) Dog_ PRDM11 ( ortholog_one2one ) GuineaPig_ PRDM11 ( ortholog_one2one ) Macaque_ PRDM11 ( ortholog_one2one ) Mouse_ Prdm11 ( ortholog_one2one ) Pig_ PRDM11 ( ortholog_one2one ) Rat_ Prdm11 ( ortholog_one2one ) Rabbit_ PRDM11 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PRDM7 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in lung, including bronchial epithelial cells and airway smooth muscle cells, as well as in peripheral blood mononuclear cells. In tonsils, expressed in B-cell types, including naive B-cells, centroblasts, centrocytes and memory B-cells (at protein level). In benign hyperplastic lymph nodes, expressed in germinal center cells in both the dark and light zones, as well as in scattered cells in the mantle zone and the interfollicular area (at protein level). {ECO:0000269|PubMed:24929828, ECO:0000269|PubMed:25499759}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 3RAY (X-ray 1.73A ) |
| DBSNP | rs111724149 rs35090414 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:25499759}. Cytoplasm {ECO:0000269|PubMed:25499759}. |
| Mouse PG classification | NA |
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