| Gene Information | |
|---|---|
| Gene Name | DMXL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 3036 |
| Protein Names | DmX-like protein 2 (Rabconnectin-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000104093 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | NA |
| Gene Card | DMXL2 |
| Uniprot ID | Q8TDJ6 |
| Pfam | PF12234; PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-0.963253858) |
| Ortholog in Animals | Alpaca_ DMXL2 ( ortholog_one2one ) Dog_ DMXL2 ( ortholog_one2one ) GuineaPig_ DMXL2 ( ortholog_one2one ) Macaque_ DMXL2 ( ortholog_one2one ) Mouse_ Dmxl2 ( ortholog_one2one ) Pig_ DMXL2 ( ortholog_one2one ) Rat_ Dmxl2 ( ortholog_one2one ) Rabbit_ DMXL2 ( ortholog_one2one ) |
| Ohnologs | DMXL1 |
| Paralogs | DMXL1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35097381 rs17524906 rs16953073 rs12102203 rs35349640 rs149028181 rs372749193 |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000269|PubMed:11809763}; Peripheral membrane protein {ECO:0000269|PubMed:11809763}. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle {ECO:0000250|UniProtKB:Q8BPN8}. Note=The external layer of the inferior boundary for the hypothalamus part of the human brain (the so called median eminence (ME)) displayed a punctate pattern of expression; expression also observed in the cell bodies lining the third ventricle, in the long processes extending from these cell bodies toward the external layer of the ME, in small clear vesicles, and in large dense core vesicles. {ECO:0000250|UniProtKB:Q8BPN8}. |
| Mouse PG classification | LPG |
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